Physician Education: Bridging Clinical Research and Patient Care

Faculty Profile

Assistant Clinical Professor
David Geffen School of Medicine at University of California Los Angeles
Division of Infectious Diseases
Center for Clinical AIDS Research and Education
Los Angeles, CA

Topics of Professional Interest:
  • HIV and women: HIV in pregnancy, reproductive health, and family planning
  • HIV/antiretroviral therapy (ART) in resource-poor settings (sub-Saharan Africa): health systems, implementation, training and mentoring
  • Immune activation
Current Professional Summary:

Dr Hoffman has recently completed her adult infectious diseases training at UCLA and has joined the faculty to pursue research and clinical infectious diseases practice. Her current research focus is in the area of optimizing care for HIV-infected women. She has developed a collaboration with the Reproductive Health and HIV Research Unit (RHRU) in Johannesburg, South Africa, that evaluates outcomes of combination antiretroviral therapy in pregnant women with advanced immunosuppression. She is also involved with HIV program development in resource-poor settings and is currently serving as the UCLA-based program co-director of a PEPFAR/USAID (U.S. President’s Emergency Plan for AIDS Relief/U.S. Agency for International Development)-funded project entitled Extending Quality Improvement for HIV/AIDS in Malawi, in collaboration with Partners in Hope Medical Center. Dr. Hoffman has an interest in supporting and improving medical education in international settings, and has established a program in Malawi to offer clinical experiences for UCLA internal medicine residents.

Committees and Organizations:
  • Member, Infectious Diseases Society of America (2005-present)
  • Member, International AIDS Society (2006-present)
  • Founder, Program Director for UCLA resident physician elective training program in Malawi, Africa (2007-present)
  • Founder/Program Director: Sustainable Nutrition for Orphans and Vulnerable Children in Malawi, Central Africa. Provides education on nutrition and sustainable food sources for families caring for orphans in northern Malawi (2008-present)
  • Co-Director, UCLA Global Health Education Program (2010-present)
Honors and Awards:
  • Nomination for UCLA Faculty Teaching Award (2009)
  • Nomination for UCLA Fellow Teaching Award (2007)
  • Nomination for UCLA Fellow Teaching Award (2006)
  • Elected to the UCLA chapter of the Alpha Omega Alpha Honor Society (2000)
  • Janet M. Glasgow Memorial Achievement Citation for Academic Achievement, UCLA School of Medicine (2000)
Education:
  • Stanford University, BA (1994)
  • University of California Los Angeles, MD (2000)
  • Harvard School of Public Health, MPH (2000)
  • Harvard Combined Medicine/Pediatrics Residency Program, Internship (2000-2001)
  • Harvard Combined Medicine/Pediatrics Residency Program, Residency (2001-2004)
  • University of California Los Angeles, Fellowship, Infectious Diseases (2005-2008)
Selected Publications:
  1. Hoffman RM, Currier JS. Management of opportunistic infections in HIV/AIDS. In: Rubin RH, Young LS, eds. Clinical Approach to Infections in the Compromised Host. 5th ed. 2011. In press as of May 2011.
  2. Pilotto JH, Velasque L, Khalili R, Ismerio R, Veloso VG, Grinsztejn B, Morgado MG, Watts DH, Currier JS, Hoffman RM. Maternal outcomes after therapy for prevention of mother-to-child transmission in HIV-infected women in Brazil. Antivir Ther. In press as of Apr 2011.
  3. Hoffman RM, Black V, Technau K, et al. Effects of highly active antiretroviral therapy duration and regimen on risk for mother-to-child transmission of HIV in Johannesburg, South Africa. JAIDS. 2010;54:35-41.
  4. Currier JS, Hoffman RM. HIV-metabolic complications of HIV and antiretroviral therapy: dyslipidemia, insulin resistance, and cardiovascular disease. Clinical Care Options. Published October 1, 2009. http://www.clinicaloptions.com/inPractice/HIV/Antiretroviral%20Therapy/ch17_pt2_Dyslipidemia.aspx. Accessed May 2, 2011.
  5. Black V, Hoffman RM, Sugar CA, et al. Safety and efficacy of initiating highly active antiretroviral therapy in an integrated antenatal and HIV clinic in Johannesburg, South Africa. JAIDS. 2008;49:276-281.
  6. Hoffman RM, Currier JS. Management of antiretroviral treatment-related complications. Infect Dis Clin North Am. 2007;21:103-132.
  7. Hoffman RM, Umeh OC, Garris C, Givens N, Currier JS. Evaluation of sex differences of fosamprenavir (with and without ritonavir) in HIV-infected men and women. HIV Clin Trials. 2007;8:371-380.
  8. Hoffman RM. Post Exposure Prophylaxis (PEP) for Human Immunodeficiency Virus and Hepatitis B and C. In: Greene HL, Mushlin SB, eds. Decision Making in Medicine: An Algorithmic Approach. 3rd ed. St Louis, MO: Mosby; 2006.
  9. Hoffman RM, Landovitz RJ, Katz JT. Complications of antiretroviral therapy: Mechanisms of action, NRTIs and NNRTIs. Hosp Inf Dis. Board Review Manual. 2004;9(2):1-11.
  10. Hoffman RM, Landovitz RJ, Katz JT. Complications of antiretroviral therapy: Protease inhibitors and new antiretroviral agents. Hosp Inf Dis. Board Review Manual. 2004;9(3):1-9.

Presentations

An Advanced CME Course in HIV Pathogenesis, Antiretrovirals, and Other Selected Issues in HIV Disease Management